The Mackie ProFX16v3 is a 16-channel mixing console featuring 11 Onyx microphone preamps with 60 dB of headroom and a built-in effects engine with 24 built-in FX, making it well suited for live sound, home recording, and content creators. The integrated 2x4 USB audio interface offers high-quality 24-bit / 192 kHz recording and playback with zero-latency monitoring.

Channels 1-2 offer combo XLR-1/4" mic/line connections and a Hi-Z switch (for guitar and bass), while channels 3-11 offer XLR or 1/4" inputs. Channels 1-8 include inserts and single-knob compressors. Channels 9/10, 11/12, and 13/14 offer two 1/4" line inputs each (L and R for stereo), while channel 15/16 uses a 3.5mm stereo input. Channels 1-16 feature gain controls, a 3-band EQ, three aux sends for monitors, a dedicated FX send, pan, mute, and level faders. Engaging channel 15/16's USB 3-4 switch will override the 3.5mm input and enable the USB return from a computer. 

Each channel strip includes button selectors for Main L/R, Sub 1-2, Sub 3-4, and PFL SOLO. The master section offers dedicated faders for Main, Sub 1-2, Sub 3-4 and FX. Main output connectors include both XLR and 1/4", while sub and control room outputs use 1/4" connectors. A dedicated 1/4" TRS headphone output includes its own independent level control. Other features include an input / USB 1-2 blend control, a dedicated FX output, an FX level fader, and an FX mute, which can also be controlled via the 1/4" footswitch input.